Day 1: San Francisco - Napa Valley (1.5 Hours Drive)

• Start: San Francisco, specifically from the Fairmont Heritage Place for a luxurious kickoff.

• Drive through the beautiful Marin County and towards Wine Country.

• Stop at a vineyard for wine tasting and lunch, such as Domaine Chandon.

• Arrival in Napa, check-in at the luxurious Auberge du Soleil.

• Enjoy a private dining experience at the hotel's Michelin-starred restaurant.

Day 2: Napa Valley - Monterey (3.5 Hours Drive)

• Start the day with a sumptuous breakfast at the hotel.

• Drive through the scenic Pacific Coast Highway, stop at Carmel-by-the-Sea for lunch at a local high-end restaurant like Aubergine.

• Arrive in Monterey and check-in at the luxury hotel, the Monterey Plaza Hotel & Spa.

• Private dinner at the Monterey Bay Aquarium with a unique experience of dining while enjoying the marine life.

Day 3: Monterey - Santa Barbara (4.5 Hours Drive)

• After breakfast, continue down the Pacific Coast Highway, considered one of the most scenic drives in the world.

• Stop at Big Sur for lunch with breathtaking views at a restaurant like Nepenthe.

• Arrive in Santa Barbara and check-in at the luxury hotel, Four Seasons Resort The Biltmore Santa Barbara.

• Enjoy a final celebratory dinner at a local top-rated restaurant, such as Stonehouse.

This route offers a balance of breathtaking coastal drives, luxury accommodations, and incredible dining experiences, all while keeping driving times comfortable. This itinerary is flexible and can be adjusted according to specific interests and preferences. Each location has plenty to offer in terms of additional activities or sites to visit, which could add to the overall experience.